Talk:Minimum inhibitory concentration

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Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 27 August 2019 and 21 December 2019. Further details are available on the course page. Student editor(s): Tythomas13.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 04:14, 17 January 2022 (UTC)

Link to The Antimicrobial Index

The link to the antibiotic MIC database is NOT spam. It is useful to us microbiologists doing diagnostic work. — Preceding unsigned comment added by 116.231.52.88 (talk) 01:59, 24 July 2011 (UTC)

I have no opinion on the value of the linked page, or the appropriateness of the link. But I think that it would need to be at least placed by an editor who has a history of sensible contributions, not just by editors who do nothing but link TOKU-E pages and/or write articles about TOKU-E. Someone please look at it and say if it's appropriate. Dicklyon (talk) 04:29, 24 July 2011 (UTC)

Seems appropriate to me. 116.231.42.153 (talk) 05:06, 31 July 2011 (UTC)

I was thinking you might want to get input from an actual editor other than the anon spamming for TOKU-E. Dicklyon (talk) 07:19, 31 July 2011 (UTC)

I removed the text about "lower MIC equals a better antibiotic." A reading of the citation listed, or any other detailed source about MIC will repeatedly state that comparing susceptible MICs between antibiotics is inappropriate. Once an organism is found to be susceptible other clinical factors should be used to determine which is "better." — Preceding unsigned comment added by 70.176.19.214 (talk) 16:58, 18 July 2013 (UTC)

Copyright problem removed

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201B Edit

Hey Taivan,

Here are some edit suggestions: "MIC depends on the microorganism, the affected human being (in vivo only) or the environment in general and the antibiotic.[1]" --> I would change this to something like "MIC depends on the microorganism, the culture environment, and the antibiotic used.[1]"
This is in difference to the minimum bactericidal concentration (MBC), which is the concentration resulting in microbial death as defined by the inability to re-culture bacteria. The closer the MIC is to the MBC, the more bactericidal the compound.[4] --> This is different than
In clinics, more often than not, exact pathogens cannot be easily determined by symptoms of the patient. And, even if the pathogen is determined, different serovars of pathogens, such as Staphylococcus aureus, have differing resistances to antimicrobials, so it is hard to prescribe correct antimicrobials.[11] --> Remove
forcefully taking the MBC of the drug is detrimental to patient due to drug toxicity. antimicrobial toxicity can come in many forms, such as immune hypersensitivity and off-target toxicity.[16] --> Capitalize
As such, determining the MIC and using the best choice antimicrobials have been gaining importance. --> has
When the MBC is much higher than the MIC, forcefully taking the MBC of the drug is detrimental to patient due to drug toxicity. antimicrobial toxicity can come in many forms, such as immune hypersensitivity and off-target toxicity.[16] --> prescribing the drug at MBC
"Depending on the pathogen and antibiotics being tested, the media can be changed and/or adjusted." --> Include any specific examples from sources you may have readily available
Also, are there any other notable assays, if not, let the reader know. If there isn't much information on them - still mention them for someone else to potentially fill in.

Solid introduction to the technique overall. I might add more to the methods to be more specific about considerations when running the assay with particular bacteria or antibiotics.

Best of luck,
Willus

Hey Taivan,

First up great article. I especially like your introduction and the clinical use part. I think both are very informative and well written. I also very much enjoyed your figure description :). I agree with Willus regarding the assay part. I think its great that you included it but it could use some additional information from different sources.

Best, Markus